"Figure 1: The female mortality rate from drug poisoning increased in 2019, driving the overall rate upwards ","" "Age-standardised mortality rates for deaths related to drug poisoning, by sex, England and Wales, registered between 1993 and 2019","" "","" "Notes","1. Age-standardised mortality rates per million people, standardised to the 2013 European Standard Population. 2. Cause of death was defined using the International Classification of Diseases, Ninth Revision (ICD-9) for the years 1993 to 2000 and Tenth Revision (ICD-10) from 2001 onwards. More details can be found in the [Quality and Methodology Information](https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/methodologies/deathsrelatedtodrugpoisoninginenglandandwalesqmi). 3. Figures are for deaths registered, rather than deaths occurring in each calendar year. More details can be found in [Section 8: Death registration delays](https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsrelatedtodrugpoisoninginenglandandwales/2019registrations#death-registration-delays). 4. Figures for England and Wales include deaths of non-residents." "Unit","Age-standardised rate per million people" "","" "Year of death registration","Persons","Males","Females" "1993","42.9","51.5","34.2" "1994","45.9","56.8","35.3" "1995","49.1","63.6","34.9" "1996","50.0","67.0","33.7" "1997","54.1","72.5","36.2" "1998","56.4","75.1","37.7" "1999","58.8","81.1","37.1" "2000","55.2","77.4","33.3" "2001","58.1","80.9","35.9" "2002","52.9","72.4","33.4" "2003","49.0","64.8","33.1" "2004","52.1","70.0","34.7" "2005","50.9","70.1","32.2" "2006","47.2","65.7","29.0" "2007","48.0","69.9","26.6" "2008","53.0","75.5","31.0" "2009","51.8","76.0","28.0" "2010","49.4","68.6","30.7" "2011","47.8","64.3","31.5" "2012","46.6","61.6","31.8" "2013","52.8","73.3","32.7" "2014","59.6","80.7","38.8" "2015","65.1","91.0","39.6" "2016","65.8","91.4","40.6" "2017","66.1","89.6","42.9" "2018","76.3","105.4","47.5" "2019","76.7","104.7","49.1"